BBC: Iran has launched drones at Israel, the Israel Defense Forces (IDF) said, appearing to mark a widely anticipated reprisal attack.
The IDF said the wave could take hours to reach Israel, a distance of 1,100 miles (1,800km).
It said Israeli forces were on high alert and "monitoring all targets".
Iran had vowed to retaliate after an attack on its consulate in Syria on 1 April - for which it blamed Israel - killed several Iranian commanders.
Shortly before news of Iran's drone launch, Israeli Prime Minister Benjamin Netanyahu said Israel's "defensive systems" were deployed.
"We are ready for any scenario, both defensively and offensively. The State of Israel is strong. The IDF is strong. The public is strong."We appreciate the US standing alongside Israel, as well as the support of Britain, France and many other countries."
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